| CORE CONCEPTS | SUGGESTED GAMES |
| Descent with modification | Bios: Mesofauna, Bios: Megafauna |
| Population genetics and demography | Biosphere |
| Species distributions and niches | Biosphere, Pangea |
| Evolutionary arms races | Evolution: Climate, Darwin’s Choice, Evolution: The Beginning |
| Classical genetics | Genotype: A Mendelian Genetics Game |
| Conservation biology | Endangered** |
| Cellular biology | Cytosis: A Cellular Biology Game |
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| THE EVOLUTION OF COMPETITIVE INTERACTIONS | |
| Interspecific competition | Evolution: Climate, Darwin’s Choice, Evolution: The Beginning |
| Aposematism and mimicry | Evolution: Climate |
| Plants and herbivores | Bios: Mesofauna, Bios: Megafauna |
| Parasite-host interactions and infectious disease | Pathogenesis, Bios: Genesis |
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| THE EVOLUTION OF NOVELTY | |
| Complex characteristics | Evolution: Climate, Evolution: The Beginning |
| Rates of evolution | Oceans: Evolution: The Beginning (with modified gameplay)**** |
| Speciation and phenotypic evolution | Evolution: Climate, Darwin’s Choice, Bios Series (Genesis, Mesofauna, Megafauna) |
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| THE HISTORY OF LIFE ON EARTH | |
| The emergence of life | Bios: Genesis |
| Precambrian life | Bios: Genesis |
| The Cambrian explosion and the origins of animal diversity | Bios: Mesofauna, Bios: Megafauna |
| Mass extinctions | Bios: Mesofauna, Bios: Megafauna |
| The Cenozoic: the modern world takes shape (species and tectonic movements) | Bios: Mesofauna, Bios: Megafauna |
| The Cenozoic: Pleistocene events | Biosphere (with our materials) |
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| WHERE DID WE COME FROM? | |
| Our closest living relatives | Neanderthal, Bios: Origins |
| Our ancestry: Hominins through time | Bios: Origins |
| The human brain and language | Neanderthal |
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| SCIENCE HISTORY | |
| Charles Darwin’s voyage | On the Origin of Species |
| Alexander von Humboldt’s voyages | Humboldt’s Great Voyage*** |
| Gregory Mendel’s experiments | Genotype |
| |
| NATURAL HISTORY | Wingspan**, Inhabit the Earth |
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| TAXA FOCUS | |
| Prokaryotes and Eukaryotes | Bios: Genesis |
| Plants | Bios: Genesis, Bios: Mesofauna, Bios: Megafauna, On the Origins of Species |
| Mollusks | Bios: Megafauna |
| Insects | Bios: Mesofauna, Dominant Species, On the Origins of Species |
| Fishes | A.D.A.P.T, Oceans, Dominant Species Marine, On the Origins of Species |
| Mammals | Bios: Megafauna, Endangered, Biosphere, Evolution series*, On the Origins of Species, Dominant Species |
| Reptiles | Bios: Megafauna, Biosphere, Evolution series*, Dominant Species, On the Origins of Species |
| Birds | Evolution (w/ flight Expansion)*, Dominant Species, Wingspan, On the Origins of Species, Biosphere |
| Amphibians | Pangea, Dominant Species |
| Humans | Bios: Origins, Neanderthal, Greenland, Endangered |
| Extinct taxa | Evo (taxa: dinosaurs), Bios Series (many taxa represent key evolutionary milestones that are now extinct) |